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MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma

SIMPLE SUMMARY: Glioblastoma, the brain tumour with highest prevalence and lethality, exhibits a characteristic glycolytic phenotype with increased lactate production. Recently, we reported a MCT1 overexpression in GBMs tumours, being associated to tumour growth and aggressiveness. Thus, we aimed to...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancers (Basel)
Prif Awduron: Miranda-Gonçalves, Vera, Gonçalves, Céline S., Granja, Sara, Vieira de Castro, Joana, Reis, Rui M., Costa, Bruno M., Baltazar, Fátima
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8306807/
https://ncbi.nlm.nih.gov/pubmed/34298681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13143468
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