Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics

The RON tyrosine kinase receptor is under investigation as a novel target in pancreatic cancer. While RON mutations are uncommon, RON isoforms are produced in cancer cells via a variety of mechanisms. In this study we sought to: 1) characterize RON isoform expression in pancreatic cancer, 2) investi...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Mose, Evangeline, Cheng, Peter, Holman, Patrick, Howard, Haleigh, Miyamoto, Jaclyn, Porras, Paula, Walterscheid, Zakk, Schultz-Fademrecht, Carsten, Esdar, Christina, Schadt, Oliver, Eickhoff, Jan, Lowy, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216774/
https://ncbi.nlm.nih.gov/pubmed/27323855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10009
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