A novel protein isoform of the RON tyrosine kinase receptor transforms human pancreatic duct epithelial cells

The MST1R gene is overexpressed in pancreatic cancer producing elevated levels of the RON tyrosine kinase receptor protein. While mutations in MST1R are rare, alternative splice variants have been previously reported in epithelial cancers. We report the discovery of a novel RON isoform discovered in...

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Publicado no:Oncogene
Main Authors: Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Howard, Haleigh, Mose, Evangeline, Lam, Raymond, Holman, Patrick, Miyamoto, Jaclyn, Walterscheid, Zakk, Lowy, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837108/
https://ncbi.nlm.nih.gov/pubmed/26477314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.384
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