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Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling

The seeding of tumor cells is a critical step in the process of metastasis, but whether and how the microenvironment of target organs affects metastatic seeding remain largely unknown. Based on cell and mouse models, we found that the metastatic seeding and outgrowth of tumor cells were significantl...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhang, Chong, Wu, Mengzhi, Zhang, Lizhen, Shang, Li-Ru, Fang, Jian-Hong, Zhuang, Shi-Mei
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216754/
https://ncbi.nlm.nih.gov/pubmed/27329720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10157
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