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Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury

This study was undertaken to elucidate whether and how autophagy was regulated in aldosterone (Aldo)-induced podocyte injury and to examine its role in this model both in vitro and in vivo. In cultured podocytes, Aldo increased autophagy flux as indicated by the enhanced expression of LC3-II/LC3-I a...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Wang, Bin, Ding, Wei, Zhang, Minmin, Li, Hongmei, Guo, Honglei, Lin, Lilu, Chen, Jing, Gu, Yong
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216726/
https://ncbi.nlm.nih.gov/pubmed/27244896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9644
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