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Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury

This study was undertaken to elucidate whether and how autophagy was regulated in aldosterone (Aldo)-induced podocyte injury and to examine its role in this model both in vitro and in vivo. In cultured podocytes, Aldo increased autophagy flux as indicated by the enhanced expression of LC3-II/LC3-I a...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Wang, Bin, Ding, Wei, Zhang, Minmin, Li, Hongmei, Guo, Honglei, Lin, Lilu, Chen, Jing, Gu, Yong
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216726/
https://ncbi.nlm.nih.gov/pubmed/27244896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9644
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