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Mitochondrial reactive oxygen species-mediated NLRP3 inflammasome activation contributes to aldosterone-induced renal tubular cells injury

Aldosterone (Aldo) is an independent risk factor for chronic kidney disease (CKD), and although Aldo directly induces renal tubular cell injury, the underlying mechanisms remain unclear. NLRP3 inflammasome and mitochondrial reactive oxygen species (ROS) have recently been implicated in various kinds...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Ding, Wei, Guo, Honglei, Xu, Chengyan, Wang, Bin, Zhang, Minmin, Ding, Feng
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951227/
https://ncbi.nlm.nih.gov/pubmed/27014913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8243
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