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Neuregulin expression in solid tumors: Prognostic value and predictive role to anti-HER3 therapies

BACKGROUND: Neuregulins (NRG) are a family of epidermal growth factor ligands which act through binding to HER3 and HER4 receptors. NRGs are widely expressed in solid tumors. Their prognostic significance or their role as predictors of benefit from anti-HER3 therapy is not known. RESULTS: Of 29 incl...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Ocaña, Alberto, Díez-González, Laura, Esparís-Ogando, Azucena, Montero, Juan Carlos, Amir, Eitan, Pandiella, Atanasio
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216704/
https://ncbi.nlm.nih.gov/pubmed/27074567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8648
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