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Neuregulin expression in solid tumors: Prognostic value and predictive role to anti-HER3 therapies

BACKGROUND: Neuregulins (NRG) are a family of epidermal growth factor ligands which act through binding to HER3 and HER4 receptors. NRGs are widely expressed in solid tumors. Their prognostic significance or their role as predictors of benefit from anti-HER3 therapy is not known. RESULTS: Of 29 incl...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ocaña, Alberto, Díez-González, Laura, Esparís-Ogando, Azucena, Montero, Juan Carlos, Amir, Eitan, Pandiella, Atanasio
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216704/
https://ncbi.nlm.nih.gov/pubmed/27074567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8648
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