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The Extracellular Linker of pro-Neuregulin-α2c Is Required for Efficient Sorting and Juxtacrine Function

The neuregulins (NRGs) play important roles in animal physiology, and their disregulation has been linked to diseases such as cancer or schizophrenia. The NRGs may be produced as transmembrane proteins (proNRGs), even though they lack an N-terminal signal sequence. This raises the question of how NR...

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Hlavní autoři: Montero, Juan C., Rodríguez-Barrueco, Ruth, Yuste, Laura, Juanes, Pedro P., Borges, Joana, Esparís-Ogando, Azucena, Pandiella, Atanasio
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783780/
https://ncbi.nlm.nih.gov/pubmed/17108327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0511
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