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The Extracellular Linker of pro-Neuregulin-α2c Is Required for Efficient Sorting and Juxtacrine Function

The neuregulins (NRGs) play important roles in animal physiology, and their disregulation has been linked to diseases such as cancer or schizophrenia. The NRGs may be produced as transmembrane proteins (proNRGs), even though they lack an N-terminal signal sequence. This raises the question of how NR...

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Detalhes bibliográficos
Main Authors: Montero, Juan C., Rodríguez-Barrueco, Ruth, Yuste, Laura, Juanes, Pedro P., Borges, Joana, Esparís-Ogando, Azucena, Pandiella, Atanasio
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783780/
https://ncbi.nlm.nih.gov/pubmed/17108327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0511
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