From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells

In the past decades, experimental rodent models developed to study the pathogenesis of human colorectal cancer (CRC) generally employed synthetic chemical carcinogens or genetic manipulation. Our lab, in order to establish a more physiologically relevant CRC model, recently developed a colon carcino...

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Bibliografiska uppgifter
I publikationen:Toxicol Sci
Huvudupphovsmän: Chen, Jayson X., Wang, Hong, Liu, Anna, Zhang, Lanjing, Reuhl, Kenneth, Yang, Chung S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2017
Ämnen:
Colon Carcinogenesis in Mice Expressing the Human Form of CYP1A
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216652/
https://ncbi.nlm.nih.gov/pubmed/27664423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw190
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