From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells

In the past decades, experimental rodent models developed to study the pathogenesis of human colorectal cancer (CRC) generally employed synthetic chemical carcinogens or genetic manipulation. Our lab, in order to establish a more physiologically relevant CRC model, recently developed a colon carcino...

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Detaylı Bibliyografya
Yayımlandı:Toxicol Sci
Asıl Yazarlar: Chen, Jayson X., Wang, Hong, Liu, Anna, Zhang, Lanjing, Reuhl, Kenneth, Yang, Chung S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Colon Carcinogenesis in Mice Expressing the Human Form of CYP1A
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216652/
https://ncbi.nlm.nih.gov/pubmed/27664423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw190
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