From the Cover: PhIP/DSS-Induced Colon Carcinogenesis in CYP1A-Humanized Mice and the Possible Role of Lgr5+ Stem Cells

In the past decades, experimental rodent models developed to study the pathogenesis of human colorectal cancer (CRC) generally employed synthetic chemical carcinogens or genetic manipulation. Our lab, in order to establish a more physiologically relevant CRC model, recently developed a colon carcino...

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Bibliografiset tiedot
Julkaisussa:Toxicol Sci
Päätekijät: Chen, Jayson X., Wang, Hong, Liu, Anna, Zhang, Lanjing, Reuhl, Kenneth, Yang, Chung S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Colon Carcinogenesis in Mice Expressing the Human Form of CYP1A
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216652/
https://ncbi.nlm.nih.gov/pubmed/27664423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw190
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