Dystrophin contains multiple independent membrane-binding domains

Dystrophin is a large sub-sarcolemmal protein. Its absence leads to Duchenne muscular dystrophy (DMD). Binding to the sarcolemma is essential for dystrophin to protect muscle from contraction-induced injury. It has long been thought that membrane binding of dystrophin depends on its cysteine-rich (C...

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Publicado en:Hum Mol Genet
Autores principales: Zhao, Junling, Kodippili, Kasun, Yue, Yongping, Hakim, Chady H., Wasala, Lakmini, Pan, Xiufang, Zhang, Keqing, Yang, Nora N., Duan, Dongsheng, Lai, Yi
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216612/
https://ncbi.nlm.nih.gov/pubmed/27378693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw210
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