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Dystrophin contains multiple independent membrane-binding domains
Dystrophin is a large sub-sarcolemmal protein. Its absence leads to Duchenne muscular dystrophy (DMD). Binding to the sarcolemma is essential for dystrophin to protect muscle from contraction-induced injury. It has long been thought that membrane binding of dystrophin depends on its cysteine-rich (C...
Shranjeno v:
| izdano v: | Hum Mol Genet |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5216612/ https://ncbi.nlm.nih.gov/pubmed/27378693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw210 |
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