High‐Resolution NMR Determination of the Dynamic Structure of Membrane Proteins

(15)N spin‐relaxation rates are demonstrated to provide critical information about the long‐range structure and internal motions of membrane proteins. Combined with an improved calculation method, the relaxation‐rate‐derived structure of the 283‐residue human voltage‐dependent anion channel revealed...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Jaremko, Mariusz, Jaremko, Łukasz, Villinger, Saskia, Schmidt, Christian D., Griesinger, Christian, Becker, Stefan, Zweckstetter, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216445/
https://ncbi.nlm.nih.gov/pubmed/27461260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201602639
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