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Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis

AIMS: Aortic valve stenosis (AS) is the most common valvulopathy and is characterized by inflammation, extracellular matrix (ECM) remodelling and calcification, causing a narrowing of the valve and the consequential obstruction of the cardiac outflow. Although intraleaflet haemorrhage is associated...

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Detalles Bibliográficos
Publicado en:Eur Heart J
Main Authors: Laguna-Fernandez, Andres, Carracedo, Miguel, Jeanson, Gregoire, Nagy, Edit, Eriksson, Per, Caligiuri, Giuseppina, Franco-Cereceda, Anders, Bäck, Magnus
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216198/
https://ncbi.nlm.nih.gov/pubmed/27091952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw122
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