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Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis

AIMS: Aortic valve stenosis (AS) is the most common valvulopathy and is characterized by inflammation, extracellular matrix (ECM) remodelling and calcification, causing a narrowing of the valve and the consequential obstruction of the cardiac outflow. Although intraleaflet haemorrhage is associated...

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Vydáno v:Eur Heart J
Hlavní autoři: Laguna-Fernandez, Andres, Carracedo, Miguel, Jeanson, Gregoire, Nagy, Edit, Eriksson, Per, Caligiuri, Giuseppina, Franco-Cereceda, Anders, Bäck, Magnus
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216198/
https://ncbi.nlm.nih.gov/pubmed/27091952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehw122
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