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Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification

Aortic valve stenosis (AVS), a consequence of increased fibrosis and calcification of the aortic valve leaflets, causes progressive narrowing of the aortic valve. Proteoglycans, structural components of the aortic valve, accumulate in regions with fibrosis and moderate calcification. Particularly, p...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Artiach, Gonzalo, Carracedo, Miguel, Seime, Till, Plunde, Oscar, Laguna-Fernandez, Andres, Matic, Ljubica, Franco-Cereceda, Anders, Bäck, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7140654/
https://ncbi.nlm.nih.gov/pubmed/32168892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9030684
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