Genetic Associations with Valvular Calcification and Aortic Stenosis

BACKGROUND: Limited information is available regarding genetic contributions to valvular calcification, which is an important precursor of clinical valve disease. METHODS: We determined genomewide associations with the presence of aorticvalve calcification (among 6942 participants) and mitral annula...

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Autori principali: Thanassoulis, George, Campbell, Catherine Y., Owens, David S., Smith, J. Gustav, Smith, Albert V., Peloso, Gina M., Kerr, Kathleen F., Pechlivanis, Sonali, Budoff, Matthew J., Harris, Tamara B., Malhotra, Rajeev, O’Brien, Kevin D., Kamstrup, Pia R., Nordestgaard, Børge G., Tybjaerg-Hansen, Anne, Allison, Matthew A., Aspelund, Thor, Criqui, Michael H., Heckbert, Susan R., Hwang, Shih-Jen, Liu, Yongmei, Sjogren, Marketa, van der Pals, Jesper, Kälsch, Hagen, Mühleisen, Thomas W., Nöthen, Markus M., Cupples, L. Adrienne, Caslake, Muriel, Di Angelantonio, Emanuele, Danesh, John, Rotter, Jerome I., Sigurdsson, Sigurdur, Wong, Quenna, Erbel, Raimund, Kathiresan, Sekar, Melander, Olle, Gudnason, Vilmundur, O’Donnell, Christopher J., Post, Wendy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766627/
https://ncbi.nlm.nih.gov/pubmed/23388002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1109034
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