Penetrance of NOD2/CARD15 genetic variants in the general population

BACKGROUND: In case–control studies of Europeans, heterozygosity for Arg702Trp(rs2066844), Gly908Arg(rs2066845) and Leu1007fsinsC(rs5743293) on the NOD2/CARD15 gene is associated with a 2-fold greater risk of Crohn disease, whereas homozygosity or compound heterozygosity is associated with a 17-fold...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yazdanyar, Shiva, Kamstrup, Pia R., Tybjærg-Hansen, Anne, Nordestgaard, Børge G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Canadian Medical Association 2010
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855913/
https://ncbi.nlm.nih.gov/pubmed/20371648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.090684
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