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Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population

Homozygosity for mutations in ABC transporter A1 (ABCA1) causes Tangier disease, a rare HDL-deficiency syndrome. Whether heterozygosity for genetic variation in ABCA1 also contributes to HDL cholesterol (HDL-C) levels in the general population is presently unclear. We determined whether mutations or...

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Bibliografiska uppgifter
Huvudupphovsmän: Frikke-Schmidt, Ruth, Nordestgaard, Børge G., Jensen, Gorm B., Tybjærg-Hansen, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2004
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC524222/
https://ncbi.nlm.nih.gov/pubmed/15520867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420361
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