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Penetrance of NOD2/CARD15 genetic variants in the general population
BACKGROUND: In case–control studies of Europeans, heterozygosity for Arg702Trp(rs2066844), Gly908Arg(rs2066845) and Leu1007fsinsC(rs5743293) on the NOD2/CARD15 gene is associated with a 2-fold greater risk of Crohn disease, whereas homozygosity or compound heterozygosity is associated with a 17-fold...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Canadian Medical Association
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2855913/ https://ncbi.nlm.nih.gov/pubmed/20371648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/cmaj.090684 |
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