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Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

Autophagy is a cellular self-eating process essential for stress response and maintaining tissue homeostasis by lysosomal degradation of unwanted or damaged proteins and organelles. Here, we show that cells with defective mitochondria induce autophagy to promote cell survival through activating the...

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Bibliografiske detaljer
Udgivet i:Genes Dis
Main Authors: Zhao, Baozhong, Qiang, Lei, Joseph, Joy, Kalyanaraman, Balaraman, Viollet, Benoit, He, Yu-Ying
Format: Artigo
Sprog:Inglês
Udgivet: Chongqing Medical University 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215801/
https://ncbi.nlm.nih.gov/pubmed/28066797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2015.12.002
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