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Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

Autophagy is a cellular self-eating process essential for stress response and maintaining tissue homeostasis by lysosomal degradation of unwanted or damaged proteins and organelles. Here, we show that cells with defective mitochondria induce autophagy to promote cell survival through activating the...

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Detalhes bibliográficos
Publicado no:Genes Dis
Main Authors: Zhao, Baozhong, Qiang, Lei, Joseph, Joy, Kalyanaraman, Balaraman, Viollet, Benoit, He, Yu-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Chongqing Medical University 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215801/
https://ncbi.nlm.nih.gov/pubmed/28066797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2015.12.002
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