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Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival

Autophagy is a cellular self-eating process essential for stress response and maintaining tissue homeostasis by lysosomal degradation of unwanted or damaged proteins and organelles. Here, we show that cells with defective mitochondria induce autophagy to promote cell survival through activating the...

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Detalles Bibliográficos
Publicado en:Genes Dis
Autores principales: Zhao, Baozhong, Qiang, Lei, Joseph, Joy, Kalyanaraman, Balaraman, Viollet, Benoit, He, Yu-Ying
Formato: Artigo
Lenguaje:Inglês
Publicado: Chongqing Medical University 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215801/
https://ncbi.nlm.nih.gov/pubmed/28066797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2015.12.002
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