The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells

A recent study demonstrated that advanced glycation end products (AGEs) play a role in monocyte infiltration in mesangial areas in diabetic nephropathy. The Ras homolog gene family, member A Rho kinase (RhoA/ROCK) pathway plays a role in regulating cell migration. We hypothesized that the RhoA/ROCK...

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Udgivet i:Sci Rep
Main Authors: Rao, Jialing, Ye, Zengchun, Tang, Hua, Wang, Cheng, Peng, Hui, Lai, Weiyan, Li, Yin, Huang, Wanbing, Lou, Tanqi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215591/
https://ncbi.nlm.nih.gov/pubmed/28054559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39727
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