Defining Surrogate Endpoints for Clinical Trials in Severe Falciparum Malaria

BACKGROUND: Clinical trials in severe falciparum malaria require a large sample size to detect clinically meaningful differences in mortality. This means few interventions can be evaluated at any time. Using a validated surrogate endpoint for mortality would provide a useful alternative allowing a s...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Jeeyapant, Atthanee, Kingston, Hugh W., Plewes, Katherine, Maude, Richard J., Hanson, Josh, Herdman, M. Trent, Leopold, Stije J., Ngernseng, Thatsanun, Charunwatthana, Prakaykaew, Phu, Nguyen Hoan, Ghose, Aniruddha, Hasan, M. Mahtab Uddin, Fanello, Caterina I., Faiz, Md Abul, Hien, Tran Tinh, Day, Nicholas P. J., White, Nicholas J., Dondorp, Arjen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215574/
https://ncbi.nlm.nih.gov/pubmed/28052109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169307
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk