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Sequestration and Red Cell Deformability as Determinants of Hyperlactatemia in Falciparum Malaria
Background. Hyperlactatemia is a strong predictor of mortality in severe falciparum malaria. Sequestered parasitized erythrocytes and reduced uninfected red blood cell deformability (RCD) compromise microcirculatory flow, leading to anaerobic glycolysis. Methods. In a cohort of patients with falcipa...
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| Publicado no: | J Infect Dis |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4747623/ https://ncbi.nlm.nih.gov/pubmed/26494775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv502 |
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