Lataa...

Anionic Oligothiophenes Compete for Binding of X‐34 but not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain‐Derived Aβ

Deposits comprised of amyloid‐β (Aβ) are one of the pathological hallmarks of Alzheimer's disease (AD) and small hydrophobic ligands targeting these aggregated species are used clinically for the diagnosis of AD. Herein, we observed that anionic oligothiophenes efficiently displaced X‐34, a Con...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: Bäck, Marcus, Appelqvist, Hanna, LeVine, Harry, Nilsson, K. Peter R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215536/
https://ncbi.nlm.nih.gov/pubmed/27767229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201604583
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!