In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligothiophenes (LCOs) enable fluorescence imaging of these protein aggregates. Using LCOs and m...

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Bibliografiska uppgifter
I publikationen:Acta Neuropathol Commun
Huvudupphovsmän: Calvo-Rodriguez, Maria, Hou, Steven S., Snyder, Austin C., Dujardin, Simon, Shirani, Hamid, Nilsson, K. Peter R., Bacskai, Brian J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839235/
https://ncbi.nlm.nih.gov/pubmed/31703739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0832-1
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