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In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligothiophenes (LCOs) enable fluorescence imaging of these protein aggregates. Using LCOs and m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Neuropathol Commun
Egile Nagusiak: Calvo-Rodriguez, Maria, Hou, Steven S., Snyder, Austin C., Dujardin, Simon, Shirani, Hamid, Nilsson, K. Peter R., Bacskai, Brian J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839235/
https://ncbi.nlm.nih.gov/pubmed/31703739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0832-1
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