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In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy

The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligothiophenes (LCOs) enable fluorescence imaging of these protein aggregates. Using LCOs and m...

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Dettagli Bibliografici
Pubblicato in:Acta Neuropathol Commun
Autori principali: Calvo-Rodriguez, Maria, Hou, Steven S., Snyder, Austin C., Dujardin, Simon, Shirani, Hamid, Nilsson, K. Peter R., Bacskai, Brian J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6839235/
https://ncbi.nlm.nih.gov/pubmed/31703739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0832-1
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