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Generation of Human Corneal Endothelial Cells via In Vitro Ocular Lineage Restriction of Pluripotent Stem Cells

PURPOSE: We generate a renewable supply of corneal endothelial cells (CEC) from human pluripotent stem cells (PSCs) under defined culture conditions. METHODS: Corneal endothelial cell induction was driven by small molecules in a stepwise fashion of lineage specification. During the initial phase, PS...

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Publicat a:Invest Ophthalmol Vis Sci
Autors principals: Zhao, Jiagang J., Afshari, Natalie A.
Format: Artigo
Idioma:Inglês
Publicat: The Association for Research in Vision and Ophthalmology 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215466/
https://ncbi.nlm.nih.gov/pubmed/28002562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-20024
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