Human melanomas and ovarian cancers overexpressing mechanical barrier molecule genes lack immune signatures and have increased patient mortality risk

We have identified eight genes whose expression in human melanoma metastases and ovarian cancers is associated with a lack of Th1 immune signatures. They encode molecules with mechanical barrier function in the skin and other normal tissues and include filaggrin (FLG), tumor-associated calcium signa...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Salerno, Elise P., Bedognetti, Davide, Mauldin, Ileana S., Deacon, Donna H., Shea, Sofia M., Pinczewski, Joel, Obeid, Joseph M., Coukos, George, Wang, Ena, Gajewski, Thomas F., Marincola, Francesco M., Slingluff, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215363/
https://ncbi.nlm.nih.gov/pubmed/28123876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1240857
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