Topical treatment of melanoma metastases with imiquimod, plus administration of a cancer vaccine, promotes immune signatures in the metastases

INTRODUCTION: Infiltration of cancers by T cells is associated with improved patient survival and response to immune therapies; however, optimal approaches to induce T cell infiltration of tumors are not known. This study was designed to assess whether topical treatment of melanoma metastases with t...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Mauldin, Ileana S., Wages, Nolan A., Stowman, Anne M., Wang, Ena, Olson, Walter C., Deacon, Donna H., Smith, Kelly T., Galeassi, Nadedja, Teague, Jessica E., Smolkin, Mark E., Chianese‐Bullock, Kimberly A., Clark, Rachael A., Petroni, Gina R., Marincola, Francesco M., Mullins, David W., Slingluff, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037037/
https://ncbi.nlm.nih.gov/pubmed/27522582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-016-1880-z
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