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TLR2/6 agonists and interferon-gamma induce human melanoma cells to produce CXCL10

Clinical approaches to treat advanced melanoma include immune therapies, whose benefits depend on tumor-reactive T-cell infiltration of metastases. However, most tumors lack significant immune infiltration prior to therapy. Selected chemokines promote T-cell migration into tumors; thus, agents that...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Mauldin, Ileana S., Wang, Ena, Deacon, Donna H., Olson, Walter C., Bao, Yongde, Slingluff, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4497924/
https://ncbi.nlm.nih.gov/pubmed/25765738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29515
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