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Replicating Single-Cycle Adenovirus Vectors Generate Amplified Influenza Vaccine Responses

Head-to-head comparisons of conventional influenza vaccines with adenovirus (Ad) gene-based vaccines demonstrated that these viral vectors can mediate more potent protection against influenza virus infection in animal models. In most cases, Ad vaccines are engineered to be replication-defective (RD-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Crosby, Catherine M., Matchett, William E., Anguiano-Zarate, Stephanie S., Parks, Christopher A., Weaver, Eric A., Pease, Larry R., Webby, Richard J., Barry, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215357/
https://ncbi.nlm.nih.gov/pubmed/27807231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00720-16
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