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IIIa Deleted Adenovirus as a Single-Cycle Genome Replicating Vector
Replication competent adenovirus (RC-Ad) vectors mediate robust transgene expression by virtue of amplifying transgenes by replication, but also put patients at a risk of frank adenovirus infection. In contrast, E1-deleted replication defective Ad (RD-Ad) vectors are safer, but produce substantially...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125442/ https://ncbi.nlm.nih.gov/pubmed/24996029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.05.030 |
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