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Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

The 12-kDa FK506-binding protein (FKBP-12) is a cytosolic receptor for the immunosuppressants FK506 and rapamycin. Here we report the molecular cloning and subcellular localization of a 13-kDa FKBP (FKBP-13), which has a 21-amino acid signal peptide and appears to be membrane-associated. Although no...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Jin, Y J, Albers, M W, Lane, W S, Bierer, B E, Schreiber, S L, Burakoff, S J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1713687/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.15.6677
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