Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

The 12-kDa FK506-binding protein (FKBP-12) is a cytosolic receptor for the immunosuppressants FK506 and rapamycin. Here we report the molecular cloning and subcellular localization of a 13-kDa FKBP (FKBP-13), which has a 21-amino acid signal peptide and appears to be membrane-associated. Although no...

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Hlavní autoři: Jin, Y J, Albers, M W, Lane, W S, Bierer, B E, Schreiber, S L, Burakoff, S J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1991
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC52151/
https://ncbi.nlm.nih.gov/pubmed/1713687
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