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Hypoxia and antitumor CD8(+) T cells: An incompatible alliance?

T Lymphocytes face pathologically low O(2) tensions within the tumor bed at which they will have to function in order to impact on the malignancy. Recent studies highlighting the importance of O(2) and hypoxia-inducible factors for CD8(+) T-cell function and fate must now be integrated into tumor im...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Vuillefroy de Silly, Romain, Dietrich, Pierre-Yves, Walker, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214994/
https://ncbi.nlm.nih.gov/pubmed/28123871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1232236
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