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Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL‐10 secreting, poorly proliferative effector cells
CD8(+) T cells controlling pathogens or tumors must function at sites where oxygen tension is frequently low, and never as high as under atmospheric culture conditions. However, T‐cell function in vivo is generally analyzed indirectly, or is extrapolated from in vitro studies under nonphysiologic ox...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163737/ https://ncbi.nlm.nih.gov/pubmed/25929785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445284 |
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