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Quantitative [(18)F]-FMISO- PET imaging shows reduction of hypoxia following trastuzumab in a murine model of HER2+ breast cancer
PURPOSE: Evaluation of [(18)F]-FMISO-PET imaging as a metric for evaluating early response to trastuzumab therapy with histological validation in a murine model of HER2+ breast cancer. PROCEDURES: Mice with BT474, HER2+ tumors, were imaged with [(18)F]-FMISO-PET during trastuzumab therapy. Pimonidaz...
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| Опубликовано в: : | Mol Imaging Biol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214951/ https://ncbi.nlm.nih.gov/pubmed/27506906 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-0994-1 |
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