Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade

Removal of immuno-suppression has been reported to enhance antitumor immunity primed by checkpoint inhibitors. Although PD-1 blockade failed to control tumor growth in a transgenic murine neuroblastoma model, concurrent inhibition of colony stimulating factor 1 receptor (CSF-1R) by BLZ945 reprogramm...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Eissler, Nina, Mao, Yumeng, Brodin, David, Reuterswärd, Philippa, Andersson Svahn, Helene, Johnsen, John Inge, Kiessling, Rolf, Kogner, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214950/
https://ncbi.nlm.nih.gov/pubmed/28123870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1232222
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