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The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18/IL-22/STAT3 pathway

Inflammasomes are important for maintaining intestinal homeostasis, and dysbiosis contributes to the pathology of inflammatory bowel disease (IBD) and increases the risk for colorectal cancer. Inflammasome defects contribute to chronic intestinal inflammation and increase the susceptibility to colit...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Mol Immunol
Asıl Yazarlar: Ratsimandresy, Rojo A, Indramohan, Mohanalaxmi, Dorfleutner, Andrea, Stehlik, Christian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214942/
https://ncbi.nlm.nih.gov/pubmed/27524110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.35
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