טוען...
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
Lipopolysaccharide (LPS) of Gram-negative bacteria can elicit a strong immune response. Although extracellular LPS is sensed by TLR4 at the cell surface and triggers a transcriptional response, cytosolic LPS binds and activates non-canonical inflammasome caspases, resulting in pyroptotic cell death,...
שמור ב:
| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group UK
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5843631/ https://ncbi.nlm.nih.gov/pubmed/29520027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03409-3 |
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