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COPs and POPs patrol inflammasome activation
Sensing and responding to pathogens and tissue damage is a core mechanism of innate immune host defense and inflammasomes represent a central cytosolic pattern recognition receptor (PRR) pathway leading to the generation of the pro-inflammatory cytokines IL-1β and IL-18 and pyroptotic cell death tha...
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| 出版年: | J Mol Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5766406/ https://ncbi.nlm.nih.gov/pubmed/29024695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.10.004 |
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