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Prediction of pharmacokinetics and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach: A case study of caffeine and ciprofloxacin
Over the last decade, physiologically based pharmacokinetics (PBPK) application has been extended significantly not only to predicting preclinical/human PK but also to evaluating the drug-drug interaction (DDI) liability at the drug discovery or development stage. Herein, we describe a case study to...
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| Publicat a: | Korean J Physiol Pharmacol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Korean Physiological Society and The Korean Society of Pharmacology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214901/ https://ncbi.nlm.nih.gov/pubmed/28066147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2017.21.1.107 |
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