CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency.

Common variable immunodeficiency (CVI) is characterized by hypogammaglobulinemia and recurrent bacterial infections due to failure of CVI B cells to differentiate in vivo into immunoglobulin-secreting plasma cells. We hypothesized that T-cell dysfunction resulting in abnormal contact-mediated B-cell...

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Detalhes bibliográficos
Main Authors: Farrington, M, Grosmaire, L S, Nonoyama, S, Fischer, S H, Hollenbaugh, D, Ledbetter, J A, Noelle, R J, Aruffo, A, Ochs, H D
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521461/
https://ncbi.nlm.nih.gov/pubmed/7508119
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