The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co-stimulatory activity.

Signals delivered to B cells via CD40 can synergize with those provided by other B cell surface receptors to induce B cell proliferation and antibody class switching as well as modulate cytokine production and cell adhesion. Recently, it has been shown that the ligand for CD40 is a cell surface prot...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Hollenbaugh, D, Grosmaire, L S, Kullas, C D, Chalupny, N J, Braesch-Andersen, S, Noelle, R J, Stamenkovic, I, Ledbetter, J A, Aruffo, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC557004/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1385114/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1992.tb05530.x
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