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A total synthesis of (−)-Hortonone C

A total synthesis of the cytotoxic terpenoid hortonone C was accomplished and its absolute stereochemistry confirmed. Intermediate (+)-4 was synthesized using either an asymmetric conjugate addition strategy, or by elaboration of the Hajos-Parrish ketone. Reduction of (+)-4 under dissolving-metal co...

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Detalhes bibliográficos
Publicado no:Tetrahedron
Main Authors: Niroula, Doleshwar, Hallada, Liam P., Rogelj, Snezna, Tello-Aburto, Rodolfo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214569/
https://ncbi.nlm.nih.gov/pubmed/28066031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2016.12.013
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