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Lung vaso-occlusion in sickle cell disease mediated by arteriolar neutrophil-platelet microemboli
In patients with sickle cell disease (SCD), the polymerization of intraerythrocytic hemoglobin S promotes downstream vaso-occlusive events in the microvasculature. While vaso-occlusion is known to occur in the lung, often in the context of systemic vaso-occlusive crisis and the acute chest syndrome,...
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| Veröffentlicht in: | JCI Insight |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5214368/ https://ncbi.nlm.nih.gov/pubmed/28097236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.89761 |
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