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Quantitative intravital two-photon excitation microscopy reveals absence of pulmonary vaso-occlusion in unchallenged Sickle Cell Disease mice

Sickle cell disease (SCD) is a genetic disorder that leads to red blood cell (RBC) sickling, hemolysis and the upregulation of adhesion molecules on sickle RBCs. Chronic hemolysis in SCD results in a hyper-inflammatory state characterized by activation of circulating leukocytes, platelets and endoth...

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Detalhes bibliográficos
Publicado no:Intravital
Main Authors: Bennewitz, Margaret F, Watkins, Simon C, Sundd, Prithu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435611/
https://ncbi.nlm.nih.gov/pubmed/25995970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/intv.29748
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