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Lamin B1 mediated demyelination: Linking Lamins, Lipids and Leukodystrophies

Autosomal Dominant Leukodystrophy (ADLD), a fatal adult onset demyelinating disorder, is the only human disease that has been linked to mutations of the nuclear lamina protein, lamin B1, and is primarily caused by duplications of the LMNB1 gene. Why CNS myelin is specifically targeted and the mechan...

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Sonraí Bibleagrafaíochta
Foilsithe in:Nucleus
Príomhúdar: Padiath, Quasar S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214339/
https://ncbi.nlm.nih.gov/pubmed/27854160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1260799
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